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      Gazans face threat of cholera and other infectious diseases, says Oxfam

      Israel turning Gaza into ‘graveyard of children and starving’, UNRWA chief

      “ELECTION INTERFERENCE, KANGAROO COURT!” Trump says on indictment charges

      US court rules against Trump’s birthright citizenship order

      Gaza death toll, 3000 children among 7028 casulties

      Gaza civil defence says 52 killed by Israeli forces

      Pakistan hopes to secure eighth term in UNSC

      Pakistan warns against Indian weaponisation of water at UN

      Israeli forces killed 50 rushing to humanitarian aid trucks, says Gaza medic

      20 killed in Israeli air strikes on Gaza

      Pakistan condoles martyrdom of 12 Turkish soldiers in methane gas poison

      Pakistan condoles martyrdom of 12 Turkish soldiers in methane gas poison

      Pakistan urges UNSC to stop Israeli aggression against Iran

      Terrorism inflating from Afghanistan serious threat to neighbours, Pakistan warns UN

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      PM applauds FBR for collecting record tax revenue

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      I celebrate my voice through my voice, says Miss Pakistan World Mia Sadique

      I celebrate my voice through my voice, says Miss Pakistan World Mia Sadique

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      Humaira Asghar’s family refuses to receive her body

      Humaira Asghar’s initial post-mortem report revealed

      Murder allegations surface about mysterious death of actress Humaira Asghar

      Murder allegations surface about mysterious death of actress Humaira Asghar

      Humaira Asghar’s family refuses to receive her body

      Humaira Asghar’s family refuses to receive her body

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      The Odyssey trailer sparks online backlash

      The Odyssey trailer sparks online backlash

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      Voice of Sindh
      Home HEALTH

      WHO recommends new, cheaper malaria vaccine for children

      Web Desk by Web Desk
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      The World Health Organization (WHO) has recommended an affordable, mass-produced malaria vaccine developed by the University of Oxford, in a major development against the life-threatening disease spread to humans by some mosquitoes.

      Malaria, a major global health issue, primarily affects babies and infants and has been a significant problem for over a century. However, agreements are already in place to produce over 100 million annual doses of the new vaccine — R21.

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      The disease is caused by a complex parasite, spread by blood-sucking mosquitoes, which is more sophisticated than a virus due to its shape-shifting inside the human body, making it difficult to build immunity naturally and develop a vaccine against it.

      It is almost two years to the day since the first vaccine — called RTS,S and developed by GSK — was backed by the WHO, BBC reported.

      Dr Tedros Adhanom Ghebreyesus, director-general of the WHO, said: “I used to dream of the day we would have a safe and effective vaccine against malaria, now we have two.”

      The UN health body stated that both vaccines were “very similar” in effectiveness, but the key difference was the University of Oxford’s ability to manufacture R21 at a massive scale.

      Additionally, the Serum Institute of India, the world’s largest vaccine manufacturer, plans to produce over 100 million doses annually and plans to increase to 200 million, despite only having 18 million RTS,S doses currently available.

      The WHO said the new R21 vaccine would be a “vital additional tool”. Each dose costs $2-4 and four doses are needed per person which is about half the price of RTS,S.

      While the two malaria vaccines share similar technologies and target the same stage of the parasite’s lifecycle, the newer vaccine is easier to manufacture due to its smaller dose and simpler adjuvant.

      In 2021, there were 247 million cases of malaria and 619,000 people died, most of them children under the age of five. More than 95% of malaria is found in Africa.

      While discussing the potential of the vaccine, Dr Matshidiso Moeti, the WHO regional director for Africa, said: “This second vaccine holds real potential to close the huge demand-and-supply gap.

      “Delivered to scale and rolled out widely, the two vaccines can help bolster malaria prevention, control efforts and save hundreds of thousands of young lives.”

      The R21 vaccine, despite not being subjected to a standard scientific review process, has been found to be 75% effective in preventing malaria in seasonal areas, according to data published online.

      The WHO’s strategic advisory group of experts suggests that malaria vaccine effectiveness is lower in areas where the parasite is present all year round, comparable to the first vaccine’s effectiveness in seasonal areas.

      Prof Sir Adrian Hill, director of the Jenner Institute in Oxford where R21 was developed, said: “The vaccine is easily deployable, cost-effective and affordable, ready for distribution in areas where it is needed most, with the potential to save hundreds of thousands of lives a year.”

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      Voice of Sindh is an initiative designed to uncover the untold stories of Sindh. It aims to preserve and promote the diverse culture, heritage, history, and traditions that make Sindh the bastion of pluralism and progress.

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